Sconce Industrial Vintage Loft Steampunk Lamp Porch Pipe Water Light Wall Rustic Wall Fixtures


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Vintage Industrial Sconce Loft Rustic Wall Light Water Pipe Porch Lamp Steampunk
Condition: New: A brand-new, unused, unopened, undamaged item in its original packaging (where packaging is Colour: Black, Brushed Copper, Brushed Silver
Brand:

Electricalsone

Department: Any
Manufacturer Warranty: 3 years Light source type: E27 Edison Bulbs
Amperage: 1A Main Colour: Rustic
Style: Vintage/Retro Sensor Type: Light
Lumens: 400 lm - 799 lm Light Source: Fluorescent Tube
Material: Metal Installation Area: Indoor
Room: Porch Light Colour: Warm White
Character Family: WALL-E Type: Sconce
Lighting Technology: E27 MPN:

VINMNLPSE

Shade Shape: Pipe Lights IP Rating: IP20
Voltage: 240V Bulb Shape Code: E27




























published on tue nov 09 2021

Sconce Industrial Vintage Loft Steampunk Lamp Porch Pipe Water Light Wall Rustic Wall Fixtures

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

Sconce Industrial Vintage Loft Steampunk Lamp Porch Pipe Water Light Wall Rustic Wall Fixtures

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

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