Kit Piston Cylinder Bore Big 52MM for 7005 400 1110 372XP 372 371 365 Husqvarna Chainsaw Parts & Accs


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52MM Big Bore Cylinder Piston Kit for Husqvarna 365 371 372 372XP 1110 400 7005
Condition: New: A brand-new, unused, unopened, undamaged item in its original packaging (where packaging is Brand:

Replaces Husqvarna

Model:

Husqvarna 365 371 372 372XP Chainsaws

MPN:

Replaces 503 93 93 72

UPC:

Does Not Apply

Type: Big Bore Cylinder Kit


published on tue nov 09 2021

Kit Piston Cylinder Bore Big 52MM for 7005 400 1110 372XP 372 371 365 Husqvarna Chainsaw Parts & Accs

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

Kit Piston Cylinder Bore Big 52MM for 7005 400 1110 372XP 372 371 365 Husqvarna Chainsaw Parts & Accs

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

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