BMW For Box Storage Charging Wireless Console Center Interior Car 3 12-17 series Other Car & Truck Interior Parts


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Car Interior Center Console Wireless Charging Storage Box For BMW 3 series 12-17
Condition: New Brand:

Unbranded

Package includes: 1x wireless car charger box Fitment: BMW 3 series 2012-2017 F30 F31 F32 F34
Special Feature: Wireless Car Charger and Storage Integrated design Manufacturer Part Number:

Does Not Apply

Warranty: 6 Month Material: ABS plastic
UPC:

7148194866729













published on tue nov 09 2021

BMW For Box Storage Charging Wireless Console Center Interior Car 3 12-17 series Other Car & Truck Interior Parts

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

BMW For Box Storage Charging Wireless Console Center Interior Car 3 12-17 series Other Car & Truck Interior Parts

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

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