01 00 NEW 02 KIT SCREWS BOLTS FAIRING COMPLETE BLACK GLOSS ZX-12R ZX12R 05 04 03 Motorcycle Fairings & Bodywork


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NEW 00 01 02 03 04 05 ZX12R ZX-12R GLOSS BLACK COMPLETE FAIRING BOLTS SCREWS KIT
Condition: New Placement on Vehicle: Left, Right, Front, Rear
Make: Kawasaki Manufacturer Part Number:

BOLT KIT

Model:

ZX12R

Body & Frame Part Type: Fairings & Body Work
Model Year: 2000-2005 Part Type: Body & Frame
Brand:

GHMOTOR













published on tue nov 09 2021

01 00 NEW 02 KIT SCREWS BOLTS FAIRING COMPLETE BLACK GLOSS ZX-12R ZX12R 05 04 03 Motorcycle Fairings & Bodywork

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

01 00 NEW 02 KIT SCREWS BOLTS FAIRING COMPLETE BLACK GLOSS ZX-12R ZX12R 05 04 03 Motorcycle Fairings & Bodywork

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

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