5-Port (AMPS5E4P-AT-58) Amcrest POE+ REFURBISHED Ethernet Over Power 4-Ports Enterprise Network Switches


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Amcrest (AMPS5E4P-AT-58) 5-Port POE+ 4-Ports Power Over Ethernet REFURBISHED
Condition: Manufacturer refurbished: An item that has been professionally restored to working order by a manufacturer or UPC:

853942007879

Type: Ethernet Switch Model:

AMPS5E4P-AT-58

MPN:

AMPS5E4P-AT-58

Country/Region of Manufacture: United States
Brand:

Amcrest

Number of LAN Ports: 5
Number of Network Ports: 5




published on tue nov 09 2021

5-Port (AMPS5E4P-AT-58) Amcrest POE+ REFURBISHED Ethernet Over Power 4-Ports Enterprise Network Switches

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

5-Port (AMPS5E4P-AT-58) Amcrest POE+ REFURBISHED Ethernet Over Power 4-Ports Enterprise Network Switches

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

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