Cupid Fairy 3D Silicone -S Craft Sugar Decor Die Baking Mold Cake Fondant Mould Sugarcraft & Chocolate Molds


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3D Fairy Cupid Silicone Mould Fondant Cake Mold Baking Die Decor Sugar Craft -S
Condition: Open box: An item in excellent, new condition with no wear. The item may be missing the original packaging or Brand:

Unbranded

MPN:

Does Not Apply

Material: Silicone
Theme: Popular Characters Color:

Pink

Country/Region of Manufacture: China Type: Chocolate Mold
EAN:

Does Not Apply

Model:

Chocolate Mold

ISBN:

Does Not Apply

UPC:

Does not apply













published on tue nov 09 2021

Cupid Fairy 3D Silicone -S Craft Sugar Decor Die Baking Mold Cake Fondant Mould Sugarcraft & Chocolate Molds

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

Cupid Fairy 3D Silicone -S Craft Sugar Decor Die Baking Mold Cake Fondant Mould Sugarcraft & Chocolate Molds

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

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