SLK300 R171 Mercedes SLK280 3 SET Mounts Mount Motor Engine Transmission SLK350 Car & Truck Motor Mounts


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Mercedes R171 SLK300 SLK280 SLK350 Transmission Engine Motor Mount Mounts SET 3
Condition: New Manufacturer Part Number:

211 240 34 17 ; 2112403417

Bundle Listing: Yes Placement on Vehicle: Left, Right, Front
Fitment Type: Direct Replacement Warranty: Yes
Surface Finish: OE / OEM Part Brand: HAMBURG TECH
Other Part Number: A2112403417 ; A211 240 34 17 UPC:

Does not apply






published on tue nov 09 2021

SLK300 R171 Mercedes SLK280 3 SET Mounts Mount Motor Engine Transmission SLK350 Car & Truck Motor Mounts

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

SLK300 R171 Mercedes SLK280 3 SET Mounts Mount Motor Engine Transmission SLK350 Car & Truck Motor Mounts

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

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