MR95ZZ 5mmx9mmx3mm 5pcs Bearing Ball Radial Groove Deep Shielded Double Other Bearings & Bushings


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MR95ZZ 5mmx9mmx3mm Double Shielded Deep Groove Radial Ball Bearing 5pcs
Condition: New: A brand-new, unused, unopened, undamaged item in its original packaging (where packaging is Main Color: Silver Tone
Package Content: / Brand:

uxcell

Weight: / Model:

MR95ZZ

Inside Diameter: / Material: Bearing Steel, Rubber
ItemPackageQuantity: 1 Thickness: 3mm / 0.12"
Outside Diameter: 9mm / 0.35" Variation Theme: Size
MPN:

Does Not Apply

Manufacturer Part Number:

Does Not Apply

Size: MR95ZZ Product Name: Linear Bearing
UPC:

605322495390





published on tue nov 09 2021

MR95ZZ 5mmx9mmx3mm 5pcs Bearing Ball Radial Groove Deep Shielded Double Other Bearings & Bushings

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

MR95ZZ 5mmx9mmx3mm 5pcs Bearing Ball Radial Groove Deep Shielded Double Other Bearings & Bushings

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

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