NEW POP 220 NO FUNKO BY FIGURINE FIGURE VINYL SPIDERMAN TV & Movie Character Toys


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NEW POP SPIDERMAN VINYL FIGURE FIGURINE BY FUNKO NO 220
Condition: New: A brand-new, unused, unopened, undamaged item (including handmade items). See the seller's Character: Spiderman
Type: Figure Model:

POP

Year: 2016 Product Line: POP
Vintage: No Material: Plastic
MPN:

6001040901388P

Character Type: Superhero
Character Family: Spider-Man Colour: Red
Toy Type: Dolls, Figures & Plushies Scale: 1:6
Brand:

Disney

Character Gender: Female
Suitable For: Unisex Title: Spider-Man: Homecoming
UPC:

Does not apply

published on tue nov 09 2021

NEW POP 220 NO FUNKO BY FIGURINE FIGURE VINYL SPIDERMAN TV & Movie Character Toys

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

NEW POP 220 NO FUNKO BY FIGURINE FIGURE VINYL SPIDERMAN TV & Movie Character Toys

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

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