Disc Brake Rotor-Specialty - Street Performance; Coated Rotor Rear Right 980828 Car & Truck Brake Discs, Rotors & Hardware


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Disc Brake Rotor-Specialty - Street Performance; Coated Rotor Rear Right 980828
Condition: New Warranty: 90 Day
Brake Rotor Thickness, Discard: 1.024 IN Quantity: 1
Wheel Bolt Circle Diameter: 5.118 IN SKU: RB7:980828
Performance Level: Standard Performance Brand:

Raybestos

Brake Rotor Type: Drum-in-Hat Manufacturer Part Number:

980828

Brake Rotor Thickness, Nominal: 1.100 IN Fitment Type: Performance/Custom
Center Hole Diameter, Maximum: 3.860 IN Height, Overall: 2.950 IN
Position: Rear Right Wheel Bolt Holes, Primary: 5
Brake Rotor Diameter, Inner: 8.030 IN Wheel Bolt Hole Diameter, Maximum: 0.610 IN
Brake Rotor Diameter, Outer: 12.100 IN Interchange Part Number: PO-2024R
Rotor Braking Surface Machining Type: Uniform Brake Rotor Casting Type: Vented
Parking Brake Diameter, Inner: 7.090 IN UPC:

887213020533

published on tue nov 09 2021

Disc Brake Rotor-Specialty - Street Performance; Coated Rotor Rear Right 980828 Car & Truck Brake Discs, Rotors & Hardware

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

Disc Brake Rotor-Specialty - Street Performance; Coated Rotor Rear Right 980828 Car & Truck Brake Discs, Rotors & Hardware

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

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