Piston 12.5:1 89mm Plug 1996-2004 XR400R Honda for Filter Motorcycle Pistons, Rings & Piston Kits


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89mm 12.5:1 Piston Plug Filter for Honda XR400R 1996-2004
Condition: New UPC:

Does Not Apply

Part Number: 34-5796 Manufacturer Part Number:

34-5796

Warranty: 30 Day Brand:

Wiseco Performance Products/NGK Spark Plugs Co,. Ltd/Uni Filter

Product Photo: Generic Product Representation Year: 1996-2004
Bundle Listing: Yes Make: Honda
Warranty Detail: Warranty - material/workmanship. Normal wear not covered Model:

XR400R

published on tue nov 09 2021

Piston 12.5:1 89mm Plug 1996-2004 XR400R Honda for Filter Motorcycle Pistons, Rings & Piston Kits

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

Piston 12.5:1 89mm Plug 1996-2004 XR400R Honda for Filter Motorcycle Pistons, Rings & Piston Kits

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

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