Oregon Mulching Blade Husqvarna John Deere 61" D18036 522936601 GDU10232 3PACK Lawn Mower Parts & Accessories


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Oregon Mulching Blade Husqvarna John Deere 61" D18036 522936601 GDU10232 3PACK
Condition: New: A brand-new, unused, unopened, undamaged item in its original packaging (where packaging is Type: Blade
Brand:

Oregon

Country/Region of Manufacture: Unknown
MPN:

539105711, 539109755, 574481301, 602439, 602439X

Color:

Black

Power Source: NA Make: Bobcat, Gravely, Husqvarna, Hustler, Snapper
Model:

JS60 JS63 Pro-Walk Pro-Stance Morgan Stallion R61R

Part Type: Blade
Custom Bundle: No Models: JS60 JS63 Pro-Walk Pro-Stance Morgan Stallion R61R
Modified Item: No Genuine OEM: No
UPC:

Does not apply

published on tue nov 09 2021

Oregon Mulching Blade Husqvarna John Deere 61" D18036 522936601 GDU10232 3PACK Lawn Mower Parts & Accessories

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

Oregon Mulching Blade Husqvarna John Deere 61" D18036 522936601 GDU10232 3PACK Lawn Mower Parts & Accessories

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

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