CIVIC HONDA 16" WHEEL 64054 2015 2014 2013 ORIGINAL OEM FACTORY RIM Wheels


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16" HONDA CIVIC WHEEL RIM FACTORY OEM ORIGINAL 2013 2014 2015 64054
Condition: Remanufactured Items Included:: Wheel Only
Surface Finish: MACHINED FACE w/ BLACK INLAY Items NOT included:: Center Caps, Inserts and TPMS sensors!
Manufacturer Part Number:

42700TR3C93

Bundle Listing: Yes
Other Part Number: 42700TR3C91 42700TR3A92 Interchange Part Number: 64054
Brand:

Honda

Type: OEM
published on tue nov 09 2021

CIVIC HONDA 16" WHEEL 64054 2015 2014 2013 ORIGINAL OEM FACTORY RIM Wheels

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

CIVIC HONDA 16" WHEEL 64054 2015 2014 2013 ORIGINAL OEM FACTORY RIM Wheels

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

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