HD LED 8 CCD Vision Night Camera Parking Backup Reverse View Rear Car Waterproof Other Car Security Equipment


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8 LED HD CCD Waterproof Car Rear View Reverse Backup Parking Camera Night Vision
Condition: New Brand:

Unbranded

View Wide Angle: 170 degrees Manufacturer Part Number:

Does Not Apply

Power supply: DC 12V Placement on Vehicle: Rear
Video system: PAL / NTSC Warranty: 1 Year
Waterproof index: IP68 UPC:

Does not apply













published on tue nov 09 2021

HD LED 8 CCD Vision Night Camera Parking Backup Reverse View Rear Car Waterproof Other Car Security Equipment

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

HD LED 8 CCD Vision Night Camera Parking Backup Reverse View Rear Car Waterproof Other Car Security Equipment

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

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