Thermal Insulated Bedroom Coverings Window Panels 2 Curtains Blackout Grommet Curtains, Drapes & Valances


  1. Home
  2. Thermal Insulated Bedroom Coverings Window Panels 2 Curtains Blackout Grommet
  1. facebook
  2. twitter
  3. linkedin
  4. pinterest
Thermal Insulated Grommet Blackout Curtains 2 Panels Window Coverings Bedroom
Condition: New: A brand-new, unused, unopened, undamaged item in its original packaging (where packaging is Manufacturer: NICETOWN
MPN:

Does not apply

Model:

FBA_NTGMBLKSLD24263C1

Item model number: FBA_NTGMBLKSLD24263C1 Brand:

NICETOWN

Shipping Weight: 2.45 pounds UPC:

7445011114149

Product Dimensions: 63 x 42 x 0.1 inches ISBN:

Does not apply

Item Weight: 2.2 pounds EAN:

07445048925961
















published on tue nov 09 2021

Thermal Insulated Bedroom Coverings Window Panels 2 Curtains Blackout Grommet Curtains, Drapes & Valances

gandhi, s., klein, j., robertson, a., pena-hernandez, m. a.,

Thermal Insulated Bedroom Coverings Window Panels 2 Curtains Blackout Grommet Curtains, Drapes & Valances

lin, m. j., roychoudhury, p., lu, p., fournier, j., ferguson, d., mohamed bakhash, s. a., muenker, m. c., srivathsan, a., wunder, e. a., kerantzas, n., wang, w., pyle, a., wilen, c. b., ogbuagu, o., greninger ,, a. l., iwasaki, a., schulz, w. l., ko, a. i.

sars-cov-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. we present a case of an immunocompromised patient with acquired b-cell deficiency who developed an indolent, protracted course of sars-cov-2 infection. remdesivir therapy alleviated symptoms and produced a transient virologic response, but her course was complicated by recrudescence of high-grade viral shedding. whole genome sequencing identified a mutation, e802d, in the nsp12 rna-dependent rna polymerase which was not present in pre-treatment specimens. in vitro experiments demonstrated that the mutation conferred a ~6-fold increase in remdesivir ic50 but resulted in a fitness cost in the absence of remdesivir. sustained clinical and virologic response was achieved after treatment with casirivimab-imdevimab. although the fitness cost observed in vitro may limit the risk posed by e802d,

, this case illustrates the importance of monitoring for remdesivir resistance and the potential benefit of combinatorial therapies in immunocompromised patients with sars-cov-2 infection.

509
1.2k
EVGENIA.RU RSS